Ozempic

Weight-loss drugs killed my appetite for life

Sam Altman, the co-founder of OpenAI, which launched ChatGPT, is not overweight. Gay tech billionaires rarely are. Even so, as he explained in a recent interview, he was keen to try a GLP-1, one of those drugs that have revolutionised weight loss in the past five years. You can understand why he was curious. Ozempic or Mounjaro might appear to have nothing in common with artificial intelligence, but both phenomena have created a sensation that we’re entering an era of accelerating and uncontrollable change. Alas, he screwed it up. He had someone inject him with a megadose, puked all night and then lay in bed for days ‘staring at a white ceiling thinking nothing’, not only feeling no urge to eat but also no ‘desire for anything’.

Ozempic has ruined Easter

From our UK edition

It’s a funny thing, being a feminist surrounded by women on weight-loss drugs. As someone who recognises the health risks of being clinically obese, I’ve never been a fat liberationist – but pretty much all of us used to be against prescribed beauty standards. In practice this meant we would critique the harmful impacts of the ‘size zero’ or ‘heroin chic’ trends rather than obsess over having gained a few pounds over Christmas. Yet, with the rise of weight-loss jabs, skinniness has become a norm rather than a feminist discussion. And twee ideas about ‘being good’ or ‘cheating’ have been replaced by – well – feeling too nauseous to cheat at all.  Which is why Easter is a fascinating holiday in this era of weight-loss jabs.

peptides

The peptides market is exploding – but are they safe?

Two weeks before the 2024 presidential election, Robert F. Kennedy Jr. tweeted that “the FDA’s war on public health is about to end.” He then listed a host of treatments, all of which he claimed had been “aggressively suppressed” by a corrupt Big Pharma system. Two Ps – psychedelics and peptides – featured on that list of treatments, one more familiar than the other. You could be forgiven for thinking that peptides are a recent creation but they’re not. They’ve been around for a long time, but they’ve gained huge attention due to Wegovy and Ozempic.

Venezuela vs Chagos: what Britain can learn from America’s ‘audacity’

From our UK edition

50 min listen

This week: Michael and Maddie dissect Donald Trump’s audacious raid on Venezuela and ask what it reveals about power, national interest and the unravelling of the rules-based order. Was America acting like a rogue state – or simply doing what states do when their interests are at stake? And could Britain learn a thing or two from how they conduct their foreign policy, specifically with regard to the Chagos Islands? Then, closer to home, they unpack the scandal surrounding West Midlands Police and the banning of Maccabi Tel Aviv fans. Who really made the call – and what does it tell us about two-tier policing and the erosion of equal justice?

The medical emergency in the Oval Office

The buzzword in politics, in the wake of the socialist takeover of New York City, is “affordability.” That was certainly on Donald Trump’s mind today during an Oval Office announcement for cheaper GLP-1s, or, as Trump called them, “fat drugs.” Trump took brief potshots at Gavin Newsom and the Obama Presidential Library, and, of course, continued to urge pregnant women not to take Tylenol.  Commerce Secretary Howard Lutnick, when Trump called him out, said he was “not yet” on GLP-1s. “Good,” Trump said, adding “CMS administrator Mehmet Oz, he doesn’t take it” – obviously, since we can all agree Dr. Oz looks great. Trump did, however, roll call the quite large White House head of communications Steven Cheung. “He’s taking it,” Trump said.

Trump

Don’t let Serena bully you into taking the fat shot

Serena Williams is one of the world’s greatest living athletes, but in her retirement, she seems to have forgotten the basics of diet and exercise. You’ve likely seen Williams’ ad campaign for Ro, a telehealth provider that specializes in GLP-1 weight loss medications like Ozempic, Wegovy and Zepbound. In the now ubiquitous commercials, Williams tells how she personally used the drug to burn stubborn postpartum fat, a respectable 31 pounds over 8 months.“It’s not a short cut, it’s science,” reads the company’s tagline. Williams looks great – of course, of course. But just because scientists have discovered a cure for fatness doesn’t mean she still hasn’t taken the easy way out.

Serena Williams

Royal treatment, neurodiverse history & is everyone on Ozempic?

From our UK edition

45 min listen

First: a look ahead to President Trump’s state visit next week Transatlantic tensions are growing as the row over Peter Mandelson’s role provides an ominous overture to Donald Trump’s state visit next week. Political editor Tim Shipman has the inside scoop on how No. 10 is preparing. Keir Starmer’s aides are braced for turbulence. ‘The one thing about Trump which is entirely predictable is his unpredictability,’ one ventures. And government figures fear he may go off message on broadcast – he is scheduled to be interviewed by GB News. It is rare for leaders to receive a second visit, especially those in their second term. But, as Tim says, ‘Britishness is fashionable in Washington’ and no-one likes ‘royal treatment’ more than Trump.

A Spartan’s guide to body shaming

From our UK edition

Now that new drugs have allowed the government’s Fat Controller to celebrate a nation of skinnies – let us hope the drugs are not too temptingly tasty – he will not have to adopt the Spartan custom of checking their naked young men every ten days for signs of excessive thinness or corpulence. In Greek eyes, obesity was particularly associated with luxury. On their tomb paintings, Etruscans tended to depict aristocrats at dinner as very fat and even more contented. Ptolemy Alexander, a Greek king of Egypt, needed two people to support him when he left the room to relieve himself.

Joe Biden, the Democrats’ tell-tale heart

How Biden blew it Joe Biden’s final act is to serve as the Democrats’ tell-tale heart. His public appearances are a haunting reminder of the lie told by so many in their party: that there was nothing wrong with the 46th president during his time in office. Biden is on a “don’t call it a comeback” tour ahead of the release of a book from Alex Thompson and Jake Tapper that threatens to reveal the poor physical and mental state the president was in during his time in office. So far we’ve learned that Biden’s “physical deterioration was so severe in 2023 and 2024 that advisors privately discussed the possibility he’d need to use a wheelchair if he won re-election.

Could Ozempic cure your phone addiction?

From our UK edition

It’s already known for whittling down waistlines – and now Ozempic looks set to have the same effect on wine consumption. Research recently published in the journal JAMA Psychiatry found semaglutide, the weight loss medication also sold under the brand name Wegovy, reduced cravings in people with alcohol use disorder.  The study by California’s USC Institute for Addiction Science divided 48 participants into two groups and found those injected with semaglutide drank less in each sitting than those offered a placebo. It is not the first research to link the jabs – originally designed as a diabetes treatment – to lower incidence of substance abuse.

The Mar-a-Lago face-off

In all the post election danger-to-democracy commentary, one unexpected new peril has emerged: the “nationwide surge of Mar-a-Lago face." Best exemplified by demented far-right activist Laura Loomer and former Fox News host-slash-former Donald Trump Jr. squeeze Kimberly Guilfoyle, Mar-a-Lago face is a cosmetic look characterized by immense volumes of cheek filler, heavy eye shadow and enough Botox to petrify the face. The male version could be seen when Florida congressman and attorney general-nominee-for-ten-seconds Matt Gaetz stepped out at the RNC with so much Botox and foundation that he instantly became a bipartisan meme. I’d argue that Mar-a-Lago face is not taking over America anytime soon. It’s barely taking over the Republican Party.

cosmetic

Why the Super Bowl was worth watching

Minus a few big plays, the Super Bowl match-up between the Philadelphia Eagles and the Kansas City Chiefs itself was a bit of a snoozer. But everyone knows the main event is not really the main event at the Super Bowl. Prior to kickoff, there’s the panning of the cameras to show the famous folk in attendance. Taylor Swift was mercilessly booed, and she didn’t seem to know how to react to the derision. In her defense — who would? Say what you will about Swift, but having your face appearing on a jumbotron elicit jeers loud enough to be heard from inside your swanky private box must be soul-shattering, no matter how many billions you have in the bank. President Donald Trump’s appearance had the opposite effect: the crowd goes wild!

super bowl

Can an AI friend solve the loneliness epidemic?

Avi Schiffmann wants to create what he calls an “Ozempic for loneliness.” He believes Friend — his AI-powered chatbot and forthcoming wearable pendant — can address the loneliness epidemic. “I’m definitely motivated by curiosity more than anything,” he explains, “but also by how controversial the topic is. It’s just so culturally relevant.”  He wants to fill a void people feel they can’t fill elsewhere, and he wants to do it now, not years from now. AI companions are, in his words, a “very effective way” to counter isolation, a salve against the atomization we’ve lamented since the dawn of urbanization. Schiffmann reached out to me after I posted a negative review of Friend’s chatbot on my blog.

friend ai

Could Ozempic bankrupt the NHS?

From our UK edition

The NHS spends around £6.5 billion every year treating obesity. People who are overweight cost the health service twice as much as those who maintain a healthy weight. Half of all cancer cases are linked to obesity and being severely overweight significantly increases the risk of other conditions, such as diabetes, strokes and heart attacks. No public health campaign or intervention has ever worked. Obesity rates have nearly doubled in the UK since the 1990s. More than 60 per cent of adults are overweight. It’s hoped that weight-loss injections, known as GLP-1 agonists – semaglutide (also known as Wegovy or Ozempic) and the more recent market entry tirzepatide (Mounjaro) – could reverse this trend.

Johann Hari’s career-long trouble with the truth

British fabulist Johann Hari is at it again. After revealing he used Ozempic to lose forty pounds in his tell-all book, the alleged journalist still hasn’t shed his penchant for telling porkies. While the miracle drug made him “listless,” “strangely muted” and “emotionally dulled,” it hasn’t killed his energy for dreaming up facts.  In his latest book, Magic Pill: The Extraordinary Benefits and Disturbing Risks of the New Weight-Loss Drugs, Hari alleged that food critic Jay Rayner had lost pleasure in eating at even the finest Parisian establishments after taking Ozempic. The catch: Rayner has never used Ozempic or any other weight-loss drug.

johann hari

Oprah ditches WeightWatchers after shedding pounds with drugs

After twenty-five years battling her weight before a studio audience, Oprah has finally dropped those pesky forty pounds... with the help of weight-loss drugs. Now the media mogul has dropped WeightWatchers too.  Earlier this week, Oprah announced that she would be leaving the company after nearly a decade on its board of directors and starring in commercials.   “I look forward to continuing to advise and collaborate with WeightWatchers and CEO Sima Sistani in elevating the conversation around recognizing obesity as a chronic condition, working to reduce stigma and advocating for health equity,” said Oprah, who apparently no longer needs the weight-loss program.

oprah winfrey weightwatchers

Jeremy Hunt should stick to sensible pledges – it’s too late for big moves

From our UK edition

Imagine you’re Chancellor Jeremy Hunt, drafting your Autumn Statement for delivery in three weeks’ time. Bookies’ odds for a Tory general election win have moved out to six-to-one (against Labour’s dead-cert one-to-seven) following by-election wipe-outs. The Lib Dems look set to nab your South West Surrey seat if you don’t stand down anyway. And you can’t give your back-benches red-meat tax cuts because public borrowing for this year could run £30 billion higher than forecast. Releasing the pension ‘triple lock’ to save money would alienate older Tories. Inheritance tax giveaways that might please them would be campaign gold for Labour.

A new war on obesity is underway

Consume American media for more than five minutes, and sandwiched between advertisements for KFC $5 Fill-Ups and a dramatic Golden Corral short pondering the age-old question, “Chicken tenders or baby back ribs?,” you’re bound to behold at least a half-dozen ads for prescription drugs. They tend to last longer than the straight-to-the-glutton-button fast-food commercials, and they play over and over and over again (who doesn’t know the Oh, Oh, Oh, Ozempic! jingle by now?) — and airtime ain’t cheap. “When Oprah Winfrey’s bombshell interview with Prince Harry and Meghan Markle aired in March 2021, the British tuned in, and many were gobsmacked at the number of drug commercials they saw,” Vox reported earlier this year.

obesity

Is Christina Hendricks the latest Ozempic tragedy?

First, it was rumored, and denied, that the Kardashians were on it. Then its usage spread all the way to Elon Musk. But now, are we seeing the real, tragic consequences of Hollywood's favorite slimming drug, Ozempic? Cockburn is devastated to hear of speculation that Christina Hendricks, also known as Joan from Mad Men, has succumbed to the latest celebrity trend. Hendricks, arguably the epitome of Rubenesque beauty in Tinseltown, caused alarm among fans online after posting a photo to Instagram following a dinner earlier this month. https://www.instagram.com/p/CuQszp2u_-M/?

christina hendricks ozempic